Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461975 | 0.96 | HTR1A (0.46) | HTR1ADRD2HTR2AADRA1DHTR1B | |
| SCHEMBL5473539 | 0.95 | HTR1A (0.46) | HTR1ADRD2HTR2AADRA1DHTR1B | |
| SCHEMBL4949576 | 0.87 | ADRA1D (0.45) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| SCHEMBL4949446 | 0.84 | ADRA1D (0.43) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| SCHEMBL4945994 | 0.83 | HTR1A (0.46) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| SCHEMBL5465734 | 0.83 | DRD2 (0.53) | HTR1ADRD2HTR2AADRA1A | |
| SCHEMBL4950532 | 0.83 | HTR1A (0.45) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| SCHEMBL4952012 | 0.81 | HTR1A (0.44) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| SCHEMBL4950274 | 0.81 | HTR1A (0.43) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| SCHEMBL5468092 | 0.80 | HTR1A (0.43) | HTR1ADRD2HTR2AADRA1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | HTR1A 3/4885DRD2 64/4885HTR2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.