Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 6/20 | 0.57 |
| ▸ | ABCC8 | Q09428 | 6/20 | 0.57 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.57 |
| ▸ | KCNJ8 | Q15842 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859948 | 0.83 | CES1 (0.50) | ABCC9ABCC8KCNJ11KCNJ8CA2 | |
| SCHEMBL5466629 | 0.81 | CES2 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CA2 | |
| SCHEMBL7804393 | 0.81 | CES1 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CA2 | |
| SCHEMBL14506290 | 0.79 | ALDH1A1 (0.52) | CA2 | |
| SCHEMBL5698489 | 0.79 | CES1 (0.50) | ABCC9ABCC8KCNJ11KCNJ8CA2 | |
| SCHEMBL2625487 | 0.79 | CES2 (0.54) | ABCC9ABCC8KCNJ11KCNJ8CA2 | |
| SCHEMBL2696027 | 0.77 | CES2 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CA2 | |
| SCHEMBL1272402 | 0.77 | CES1 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CA2 | |
| SCHEMBL22874628 | 0.76 | CES2 (0.56) | CA2CES2CES1CA1PLOD2 | |
| SCHEMBL16823 | 0.76 | CES1 (0.62) | CA2CES2CES1CA1PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070134737-A1 | Fluorophore compounds and their use in biological systems | STANFORD UNIVERSITY (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070134737-A1 | Fluorophore compounds and their use in biological systems | STANFORD UNIVERSITY (US) | 2007-06-14 | — | — | US | disclosed |
| WO-2005005956-A2 | FLUOROPHORE COMPOUNDS AND THEIR USE IN BIOLOGICAL SYSTEMS | STANFORD UNIVERSITY (US) | 2005-01-20 | — | — | WO | disclosed |
| US-20050009109-A1 | FLUOROPHORE COMPOUNDS AND THEIR USE IN BIOLOGICAL SYSTEMS | STANFORD UNIVERSITY (US) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070134737-A1 | Fluorophore compounds and their use in biological systems | DHODH, DUT, DPYD | ABCC9 3883/4885ABCC8 3359/4885KCNJ11 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.