Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.30 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922593 | 0.87 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1MAPTRECQL | |
| SCHEMBL1922594 | 0.87 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1MAPTRECQL | |
| SCHEMBL4893994 | 0.80 | TSHR (0.58) | ALDH1A1TSHR | |
| SCHEMBL3264357 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHR | |
| SCHEMBL11500859 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHR | |
| SCHEMBL4894000 | 0.80 | TSHR (0.58) | ALDH1A1TSHR | |
| SCHEMBL7125436 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTPTP4A3PTP4A1 | |
| SCHEMBL29089162 | 0.79 | TSHR (0.39) | TSHRTDP1GABRR1GABRR2BLM | |
| Fumaric Acid SCHEMBL11494667 | 0.79 | ALDH1A1 (0.79) | ALDH1A1TSHRTDP1MAPTSMN1; SMN2 | |
| Maleic Acid SCHEMBL11494666 | 0.79 | ALDH1A1 (0.79) | ALDH1A1TSHRTDP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101420923-A | Medical implant and fibrosis-inducing agent | ANGIOTECH INT AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| CN-101227935-A | Compositions and methods for treating diverticulum disease | ANGIOTECH INT AG (CH) | 2008-07-23 | — | — | CN | disclosed |
| US-20070092483-A1 | Surgical adhesive compostion and process for enhanced tissue closure and healing | POLLOCK POLYMER GROUP | 2007-04-26 | — | — | US | disclosed |
| US-5350798-A | Cyanoacrylate and oxalic acid polyester | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1994-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092483-A1 | Surgical adhesive compostion and process for enhanced tissue closure and healing | MMP1, CTSF, OGFR | ALDH1A1 1498/4885TSHR 3867/4885TDP1 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.