Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.67 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.67 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.67 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.49 |
| ▸ | CFD | P00746 | 3/20 | 0.48 |
| ▸ | F11 | P03951 | 3/20 | 0.48 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479712 | 0.83 | TRPM8 (0.76) | LTA4HPLA2G2ATRPM8ADRB3MGLL | |
| SCHEMBL837542 | 0.83 | LTA4H (0.65) | LTA4HPLA2G2ATRPM8ADRB3MGLL | |
| SCHEMBL837541 | 0.83 | LTA4H (0.65) | LTA4HPLA2G2ATRPM8ADRB3MGLL | |
| SCHEMBL16714058 | 0.82 | LTA4H (0.60) | LTA4HPLA2G2ATRPM8PTGER1MGLL | |
| SCHEMBL27612134 | 0.82 | LTA4H (0.71) | LTA4HPLA2G2ATRPM8ADRB3MGLL | |
| Oxalic Acid SCHEMBL7571181 | 0.81 | LTA4H (0.62) | LTA4HPLA2G2ATRPM8PTGER1PTGER4 | |
| SCHEMBL30708156 | 0.81 | MTNR1A (0.62) | ADRB3ADRB2MTNR1AMTNR1BADRB1 | |
| SCHEMBL21808835 | 0.81 | MTNR1A (0.62) | ADRB3ADRB2MTNR1AMTNR1BADRB1 | |
| SCHEMBL30579433 | 0.80 | LTA4H (1.00) | LTA4HPLA2G2ATRPM8ADRB3 | |
| SCHEMBL5167328 | 0.80 | LTA4H (1.00) | LTA4HPLA2G2ATRPM8ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217724-B2 | Indole, indazole, and benzazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20060063762-A1 | Indole indazole and benzazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-03-23 | — | — | US | disclosed |
| EP-1514869-A1 | INDOLE, INDAZOLE, AND BENZAZOLE DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063762-A1 | Indole indazole and benzazole derivative | ADRB3, ADRA2C, ADRB2 | LTA4H 3017/4885PLA2G2A 3711/4885TRPM8 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.