SCHEMBL548017

SCHEMBL548017

[c]1ccc(C2CC3CCC2C3)cc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
SLC6A3 Q01959 8/20 0.43
SLC6A4 P31645 6/20 0.35
JAK2 O60674 3/20 0.31
JAK1 P23458 3/20 0.31
TYK2 P29597 3/20 0.31
JAK3 P52333 3/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900460 0.85 MEN1 (0.66) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL23071389 0.79 MEN1 (0.47) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL8673153 0.79 SLC6A3 (0.57) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL6053773 0.79 SLC6A3 (0.57) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL10604179 0.76 MEN1 (0.51) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL3049400 0.76 GAA (0.66) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL30501155 0.76 POLB (0.56) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL25171587 0.76 MEN1 (0.56) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL21409728 0.76 MEN1 (0.56) MEN1POLBGAAKMT2ASLC6A3
SCHEMBL23338337 0.76 POLB (0.56) MEN1POLBGAAKMT2ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583912-A Carbazole-containing aromatic amine compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2023-01-10 CN claimed
CN-112079871-A Organometallic compound, organic light emitting device including the same, and diagnostic composition including the organometallic compound 三星电子株式会社 2020-12-15 CN claimed
US-5541163-A HYPOTENSIVE AGENTS BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1996-07-30 US claimed
CN-117603249-A Triarylamine compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2024-02-27 CN disclosed
US-20220396574-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, ELECTRONIC DEVICE, ORGANIC COMPOUND, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-12-15 US disclosed
WO-2021044262-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, ELECTRONIC APPLIANCE, ORGANIC COMPOUND, AND ILLUMINATOR 株式会社半導体エネルギー研究所 2021-03-11 WO disclosed
CN-108008600-B Radiation-sensitive composition 三菱瓦斯化学株式会社 2021-02-09 CN disclosed
CN-106458824-B Method for preparing unsaturated carboxylic acid salt using aryl oxide 巴斯夫欧洲公司 2020-10-16 CN disclosed
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP disclosed
US-9897913-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-20 US disclosed
US-8110334-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-02-07 US disclosed
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
EP-2080750-A1 RADIATION-SENSITIVE COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2009-07-22 EP disclosed
EP-1804791-A1 TETRAHYDRO PYRIDINYL PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2007-07-11 EP disclosed
WO-2006049880-A1 TETRAHYDRO PYRIDINYL PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2006-05-11 WO disclosed
US-4359584-A Preparation of p-substituted, aromatic amines BASF AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION C1S, C9, RAD51 MEN1 1910/4885POLB 842/4885GAA 2887/4885
US-20220396574-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, ELECTRONIC DEVICE, ORGANIC COMPOUND, AND LIGHTING DEVICE CRY1, CYP1A1, ARNT MEN1 1634/4885POLB 3992/4885GAA 3954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.