Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487414 | 0.78 | MAPT (0.44) | ALDH1A1MAPTHPGDCYP2C19POLB | |
| SCHEMBL904258 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TUBB1MAPTHPGDCYP1A2 | |
| SCHEMBL5490961 | 0.72 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL29958505 | 0.72 | ALDH1A1 (0.52) | ALDH1A1TUBB1MAPTHPGDCYP1A2 | |
| SCHEMBL929274 | 0.72 | ALDH1A1 (0.52) | ALDH1A1TUBB1MAPTHPGDCYP1A2 | |
| SCHEMBL5483458 | 0.72 | CA2 (0.46) | TUBB1MAPTHPGDMEN1KMT2A | |
| SCHEMBL258418 | 0.72 | CA12 (0.65) | ALDH1A1TUBB1MAPTHPGDCYP1A2 | |
| SCHEMBL811943 | 0.72 | MAPK1 (0.65) | ALDH1A1TUBB1MAPTHPGDCYP1A2 | |
| SCHEMBL12326165 | 0.72 | MAPT (0.56) | ALDH1A1TUBB1MAPTHPGDCYP1A2 | |
| SCHEMBL29697819 | 0.72 | MAPK1 (0.65) | ALDH1A1TUBB1MAPTHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |