Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481495 | 0.78 | ALDH1A1 (0.47) | MAPTGAARAB9ANPC1MEN1 | |
| SCHEMBL16562863 | 0.77 | MAPT (0.41) | MAPTGAARAB9ANPC1MEN1 | |
| SCHEMBL8863220 | 0.75 | LMNA (0.46) | MAPTGAARAB9ANPC1MEN1 | |
| SCHEMBL29687129 | 0.73 | TTR (0.62) | MAPTGAARAB9ANPC1MEN1 | |
| SCHEMBL12326172 | 0.73 | PTGS2 (0.53) | GAANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL196490 | 0.73 | TTR (0.62) | MAPTGAARAB9ANPC1MEN1 | |
| SCHEMBL8832774 | 0.72 | RAB9A (0.44) | MAPTGAARAB9ANPC1MEN1 | |
| SCHEMBL1717549 | 0.72 | AHR (0.46) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL197088 | 0.71 | CA12 (0.62) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9463 | 0.71 | ACHE (0.70) | MAPTGAARAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |