Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.66 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.66 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.66 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859941 | 1.00 | LTA4H (0.66) | LTA4HPLA2G2ATRPM8SCN9AADRB3 | |
| SCHEMBL5648360 | 0.85 | LTA4H (0.69) | LTA4HPLA2G2ATRPM8ADRB3ADRB2 | |
| SCHEMBL5481516 | 0.85 | LTA4H (0.69) | LTA4HPLA2G2ATRPM8ADRB3ADRB2 | |
| SCHEMBL837541 | 0.84 | LTA4H (0.65) | LTA4HPLA2G2ATRPM8ADRB3MEN1 | |
| SCHEMBL837542 | 0.84 | LTA4H (0.65) | LTA4HPLA2G2ATRPM8ADRB3MEN1 | |
| Oxalic Acid SCHEMBL7571181 | 0.82 | LTA4H (0.62) | LTA4HPLA2G2ATRPM8ADRB3MEN1 | |
| SCHEMBL5479712 | 0.82 | TRPM8 (0.76) | LTA4HPLA2G2ATRPM8ADRB3KMT2A | |
| SCHEMBL6617826 | 0.81 | LTA4H (0.70) | LTA4HPLA2G2ATRPM8ADRB3MEN1 | |
| SCHEMBL5167328 | 0.80 | LTA4H (1.00) | LTA4HPLA2G2ATRPM8ADRB3HTR2A | |
| SCHEMBL30579433 | 0.80 | LTA4H (1.00) | LTA4HPLA2G2ATRPM8ADRB3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115412-B2 | Process for the preparation of optically active 7-substituted-3-(2-aminopropyl)indole derivatives and intermediates therefor | MERCIAN CORPORATION (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20030181732-A1 | Producing a tryptophan in the presence of a tryptophan-synthesizing enzyme originating in microorganisms, forming adrenergic receptors | MERCIAN CORPORATION (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1275730-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 7-SUBSTITUTED-3-(2-AMINOPROPYL)INDOLE DERIVATIVES AND INTERMEDIATES FOR PRODUCING THE SAME | MERCIAN CORPORATION (JP) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181732-A1 | Producing a tryptophan in the presence of a tryptophan-synthesizing enzyme originating in microorganisms, forming adrenergic receptors | TPH1, TPH2, SRR | LTA4H 223/4885PLA2G2A 2581/4885TRPM8 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.