SCHEMBL548165

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30281053	0.79	ALDH1A1 (0.39)	POLBL3MBTL1TDP1ALDH1A1KDM4E
	SCHEMBL548045	0.79	ERN1 (0.42)	TDP1ALDH1A1KDM4EMEN1KMT2A
	SCHEMBL19785604	0.74	TSHR (0.53)	L3MBTL1TDP1ALDH1A1KDM4EMEN1
	SCHEMBL4757882	0.73	ERN1 (0.45)	POLBL3MBTL1TDP1ALDH1A1KDM4E
	SCHEMBL1984171	0.73	HMGB1 (0.55)	TDP1ALDH1A1KDM4EMEN1KMT2A
	SCHEMBL30281103	0.73	MAPT (0.37)	TDP1KDM4EMEN1KMT2A
	SCHEMBL436346	0.72	ALDH1A1 (0.48)	ALDH1A1KDM4EERN1UNGPTPN2
	SCHEMBL436351	0.72	ALDH1A1 (0.48)	ALDH1A1KDM4EUNGPTPN2PTPN1
	SCHEMBL30014296	0.72	ALDH1A1 (0.48)	ALDH1A1KDM4EERN1UNGPTPN2
	SCHEMBL1816107	0.72	SRC (0.40)	POLBL3MBTL1TDP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.