Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL545561 | 0.92 | FAAH (0.38) | GPR84FAAHFFAR4FFAR1CA2 | |
| SCHEMBL548381 | 0.89 | TGFBR1 (0.35) | NFKB1TGFBR1TSHR | |
| SCHEMBL28345628 | 0.86 | PTPN1 (0.38) | TGFBR1 | |
| SCHEMBL3738357 | 0.82 | TGFBR1 (0.41) | TGFBR1TSHR | |
| SCHEMBL23761385 | 0.82 | ACE2 (0.37) | DPP7CA1CA2TGFBR1TSHR | |
| SCHEMBL28346307 | 0.81 | TGFBR1 (0.39) | TGFBR1 | |
| Lactic Acid SCHEMBL544967 | 0.81 | TGFBR1 (0.38) | GPR84FAAHFFAR1TGFBR1 | |
| SCHEMBL14931 | 0.81 | TGFBR1 (0.37) | TGFBR1TSHR | |
| SCHEMBL225597 | 0.81 | TSHR (0.50) | CA1CA2TSHR | |
| SCHEMBL29642018 | 0.81 | DPP7 (0.41) | DPP7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110220-B2 | Temperature sensitive polymers | UNIVERSITEIT UTRECHT (NL) | 2012-02-07 | — | — | US | disclosed |
| EP-1776400-B1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT VAN UTRECHT (NL) | 2009-12-23 | — | — | EP | disclosed |
| US-20080050435-A1 | Temperature Sensitive Polymers | CRISTAL DELIVERY B.V. (NL) | 2008-02-28 | — | — | US | disclosed |
| EP-1776400-A2 | TEMPERATURE SENSITIVE POLYMERS | Universiteit van Utrecht (NL) | 2007-04-25 | — | — | EP | disclosed |
| WO-2005087825-A2 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080050435-A1 | Temperature Sensitive Polymers | LCT, LDHB, LDHA | GPR84 3603/4885FAAH 951/4885FFAR4 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.