Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 10/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 9/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.43 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.43 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.43 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.43 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.43 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550889 | 0.86 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL4065289 | 0.84 | BCAT2 (0.43) | BCAT2BRD4ALDH1A1MAPTHPGD | |
| SCHEMBL28681774 | 0.82 | PLA2G2A (0.57) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL10318607 | 0.77 | ALDH1A1 (0.44) | PLA2G2APLA2G10ALDH1A1MAPTUSP2 | |
| SCHEMBL4325902 | 0.77 | PIK3CD (0.41) | CDC7 | |
| SCHEMBL529871 | 0.77 | BCAT2 (0.48) | BCAT2BRD4ALDH1A1MAPTHPGD | |
| SCHEMBL4410163 | 0.77 | BCAT2 (0.42) | BCAT2BRD4ALDH1A1MAPTHPGD | |
| SCHEMBL6528867 | 0.77 | ALDH1A1 (0.42) | PLA2G2APLA2G10ALDH1A1MAPTUSP2 | |
| SCHEMBL4937860 | 0.76 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL27475690 | 0.76 | BCAT2 (0.47) | BCAT2BRD4ALDH1A1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185148-A1 | M3 muscarinic acetylchoine receptor antagonists | CHRM3, CHRM2, CHRM5 | PLA2G2A 1836/4885PLA2G10 2587/4885PLA2G1B 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.