Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487953 | 0.97 | MEN1 (0.32) | KMT2AMEN1PABPC1 | |
| SCHEMBL5484396 | 0.82 | MEN1 (0.33) | KMT2AMEN1PABPC1 | |
| SCHEMBL5484884 | 0.82 | AGTR1 (0.36) | KMT2AMEN1PABPC1LMNASMN1; SMN2 | |
| SCHEMBL5473379 | 0.81 | GPR84 (0.33) | ACEKMT2AMEN1PABPC1LMNA | |
| SCHEMBL5481149 | 0.81 | GPR84 (0.34) | ACE2ACEKMT2AMEN1PABPC1 | |
| SCHEMBL5485623 | 0.71 | MEN1 (0.36) | KMT2AMEN1PABPC1 | |
| SCHEMBL6444607 | 0.61 | ALDH1A1 (0.48) | ACE2KMT2AMEN1CNR2 | |
| Bicarbonate SCHEMBL6439327 | 0.57 | ACE2 (0.76) | ACE2 | |
| Acetic Acid SCHEMBL8724669 | 0.55 | ACE2 (0.60) | ACE2LMNA | |
| SCHEMBL30882121 | 0.55 | GPR84 (0.61) | ACE2PTPN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | claimed |
| EP-1798234-B1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | TIANJIN TASLY GROUP CO LTD (CN) | 2012-06-13 | — | — | EP | disclosed |
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | disclosed |