Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482248 | 0.97 | ACE2 (0.33) | MEN1PABPC1KMT2A | |
| SCHEMBL5484396 | 0.83 | MEN1 (0.33) | MEN1PABPC1KMT2A | |
| SCHEMBL5477674 | 0.83 | MEN1 (0.31) | MEN1PABPC1KMT2A | |
| SCHEMBL5484884 | 0.81 | AGTR1 (0.36) | MEN1PABPC1KMT2A | |
| SCHEMBL5473379 | 0.78 | GPR84 (0.33) | MEN1PABPC1KMT2A | |
| SCHEMBL5481149 | 0.77 | GPR84 (0.34) | MEN1PABPC1KMT2A | |
| SCHEMBL5485623 | 0.72 | MEN1 (0.36) | MEN1PABPC1KMT2A | |
| SCHEMBL3861517 | 0.64 | MEN1 (0.51) | MEN1PABPC1KMT2A | |
| SCHEMBL23278619 | 0.58 | GRIA4 (0.45) | MEN1PABPC1KMT2APTGES | |
| SCHEMBL6444607 | 0.56 | ALDH1A1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | claimed |
| EP-1798234-B1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | TIANJIN TASLY GROUP CO LTD (CN) | 2012-06-13 | — | — | EP | disclosed |
| EP-1798234-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TEMOZOLOMIDE ESTER | Tianjin Tasly Group Co., Ltd. (CN) | 2007-06-20 | — | — | EP | disclosed |