Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604776 | 0.80 | CYP2D6 (0.46) | SMN1; SMN2TSHRHTTGAACYP2C9 | |
| SCHEMBL9741308 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL5474022 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL5474691 | 0.78 | OPRM1 (0.45) | SMN1; SMN2ALDH1A1HPGDCALM1 | |
| SCHEMBL6420389 | 0.77 | TLR8 (0.55) | ALDH1A1HPGD | |
| SCHEMBL5477397 | 0.75 | CALM1 (0.46) | SMN1; SMN2ALDH1A1TSHRHTTGAA | |
| SCHEMBL29277071 | 0.75 | TSHR (0.35) | SMN1; SMN2ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL17358224 | 0.72 | L3MBTL1 (0.49) | SMN1; SMN2ALDH1A1TSHRGAAMEN1 | |
| SCHEMBL3524860 | 0.72 | CYP2C9 (0.50) | SMN1; SMN2ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL1442779 | 0.72 | NPC1 (0.54) | SMN1; SMN2ALDH1A1MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | ITO MASHITO | 2007-07-19 | — | — | US | disclosed |
| EP-1718305-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | Bayer CropScience AG (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005079798-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | DPYD, DHFR, TYMP | SMN1; SMN2 3837/4885ALDH1A1 697/4885MAPT 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.