Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744009 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2GAACYP2C9CYP2C19TSHR | |
| SCHEMBL5483849 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2GAACYP2C9CYP2C19TSHR | |
| SCHEMBL7604776 | 0.80 | CYP2D6 (0.46) | SMN1; SMN2GAACYP2C9CYP2C19TSHR | |
| SCHEMBL17272795 | 0.76 | LTB4R (0.39) | GAACYP2C9CYP2C19HTTCALM1 | |
| SCHEMBL5474022 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2GAACYP2C9CYP2C19TSHR | |
| SCHEMBL5477397 | 0.75 | CALM1 (0.46) | SMN1; SMN2GAACYP2C9CYP2C19TSHR | |
| Bicarbonate SCHEMBL11028140 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2GAATSHRHTTMAPT | |
| SCHEMBL27936593 | 0.72 | CALM1 (0.48) | SMN1; SMN2CYP2C9CYP2C19TSHRHTT | |
| SCHEMBL1442779 | 0.72 | NPC1 (0.54) | SMN1; SMN2HTTMAPTKMT2AALDH1A1 | |
| Benzylthiouracil SCHEMBL2353689 | 0.72 | BCL2 (0.41) | SMN1; SMN2CALM1BCL2BCL2L1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | ITO MASHITO | 2007-07-19 | — | — | US | disclosed |
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | ITO MASHITO | 2007-07-19 | — | — | US | disclosed |
| WO-1992006965-A1 | HERBICIDAL SULFONYLUREA DERIVATIVES | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1992-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | DPYD, DHFR, TYMP | SMN1; SMN2 3837/4885GAA 2535/4885CYP2C9 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.