Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484135 | 0.82 | SLC6A4 (0.40) | OPRM1SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL5485621 | 0.72 | MAOB (0.35) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB | |
| SCHEMBL21935248 | 0.69 | ACHE (0.59) | SLC6A3SLC6A4SLC6A2MAOBMAOA | |
| SCHEMBL19830973 | 0.67 | PNMT (0.58) | OPRM1SLC6A3HSD11B1MAOBMAOA | |
| SCHEMBL21041891 | 0.65 | MAOB (0.39) | OPRM1SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL21131205 | 0.65 | SLC6A3 (0.43) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB | |
| SCHEMBL11793808 | 0.61 | OPRM1 (0.39) | OPRM1SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL9842082 | 0.61 | KDM1A (0.38) | — | |
| SCHEMBL12457116 | 0.61 | SLC6A3 (0.52) | OPRM1SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL15736884 | 0.61 | TDP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |