SCHEMBL5484457

SCHEMBL5484457

O=C(OC(=O)c1ccccc1Br)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
MEN1 O00255 3/20 0.49
F2 P00734 1/20 0.48
LMNA P02545 1/20 0.48
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
USP2 O75604 1/20 0.46
MIF P14174 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 2/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484453 0.90 KMT2A (0.49) KMT2ALMNAALDH1A1KDM4EMAPT
SCHEMBL322998 0.86 LMNA (0.58) KMT2AF2LMNAALDH1A1MAPT
SCHEMBL10804301 0.85 F2 (0.65) KMT2AMEN1F2LMNAALDH1A1
SCHEMBL25167793 0.84 KMT2A (0.49) KMT2AMEN1LMNAALDH1A1KDM4E
SCHEMBL29055923 0.84 LMNA (0.56) KMT2AF2LMNAALDH1A1MAPT
Hydrogen Peroxide SCHEMBL27952375 0.81 LMNA (0.70) KMT2AF2LMNAALDH1A1MAPT
Benzene SCHEMBL27793442 0.81 LMNA (0.70) KMT2AF2LMNAALDH1A1MAPT
SCHEMBL52413 0.81 LMNA (0.70) KMT2AF2LMNAALDH1A1MAPT
SCHEMBL3822911 0.80 ALDH1A1 (0.58) F2LMNAALDH1A1KDM4EHPGD
SCHEMBL11658581 0.79 CES2 (0.50) KMT2ALMNAALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111154083-B Phthalic anhydride polyester polyol with narrow molecular weight distribution and preparation method thereof 万华化学集团股份有限公司 2022-04-22 CN claimed
CN-111286083-A Bromine flame retardant and preparation method thereof 广州埃登达化工有限公司 2020-06-16 CN claimed
CN-111154083-A Phthalic anhydride polyester polyol with narrow molecular weight distribution and preparation method thereof 万华化学集团股份有限公司 2020-05-15 CN claimed
US-20180273819-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS COMPRISING TRIAMINES AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS LLC (US) 2018-09-27 US claimed
WO-2016179028-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS, LLC. (US) 2016-11-10 WO claimed
US-7247740-B2 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2007-07-24 US claimed
EP-1472217-B1 METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF MERCK PATENT GMBH (DE) 2007-01-24 EP claimed
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2005-04-21 US claimed
WO-2025015175-A2 HEATING, VENTILATION, AND AIR CONDITIONING (HVAC) SYSTEMS AND METHODS FOR USING SAME STASIS ENERGY GROUP, LLC (US) 2025-01-16 WO disclosed
CN-115894415-A Synthesis method of dianhydride monomer 慧迈材料科技(广东)有限公司 2023-04-04 CN disclosed
CN-115485269-A Ring-closure synthesis of macrocyclic MCL-1 inhibitor intermediates 安进公司 2022-12-16 CN disclosed
CN-111154083-B Phthalic anhydride polyester polyol with narrow molecular weight distribution and preparation method thereof 万华化学集团股份有限公司 2022-04-22 CN disclosed
CN-111286083-A Bromine flame retardant and preparation method thereof 广州埃登达化工有限公司 2020-06-16 CN disclosed
CN-111286083-A Bromine flame retardant and preparation method thereof 广州埃登达化工有限公司 2020-06-16 CN disclosed
WO-2016179028-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS, LLC. (US) 2016-11-10 WO disclosed
US-7247740-B2 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2007-07-24 US disclosed
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2005-04-21 US disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed
US-3970671-A XANTHENE, PRESSURE SENSITIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1976-07-20 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid PFKFB2, PFKFB3, PHOSPHO1 KMT2A 2984/4885MEN1 4566/4885F2 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.