Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31552901 | 1.00 | HDAC8 (0.47) | HDAC8MGAMMAPTALDH1A1GAA | |
| Nitrogen SCHEMBL27690667 | 0.96 | HDAC8 (0.44) | HDAC8MGAMMAPTALDH1A1GAA | |
| SCHEMBL16401204 | 0.76 | MGAM (0.48) | HDAC8MGAMMAPTALDH1A1GAA | |
| SCHEMBL30382206 | 0.76 | MGAM (0.48) | HDAC8MGAMMAPTALDH1A1GAA | |
| Phosphoric Acid SCHEMBL27545223 | 0.75 | HDAC8 (0.47) | HDAC8MGAMMAPTALDH1A1GAA | |
| SCHEMBL7355299 | 0.73 | ALDH1A1 (0.48) | ALDH1A1GAASMN1; SMN2KDM4E | |
| Phosphoric Acid SCHEMBL28023255 | 0.73 | NCF1 (0.47) | HDAC8MGAMMAPTALDH1A1GAA | |
| Phosphoric Acid SCHEMBL29119725 | 0.73 | NCF1 (0.47) | HDAC8MGAMMAPTALDH1A1GAA | |
| Phosphoric Acid SCHEMBL4552489 | 0.73 | BACE1 (0.76) | HDAC8MGAMMAPTALDH1A1GAA | |
| SCHEMBL1585265 | 0.73 | PGK1 (0.58) | HDAC8MGAMMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5277788-A | Twice-anodized aluminum article having an organo-phosphorus monolayer and process for making the article | ALUMINUM COMPANY OF AMERICA (US) | 1994-01-11 | — | — | US | claimed |
| EP-0244167-B1 | IMPROVED PROCESS FOR PREPARING POLY (ARYL ETHERS) AND POLY (ARYL ETHER KETONES) | AMOCO CORPORATION (US) | 1990-04-04 | — | — | EP | claimed |
| US-7176011-B2 | Lipid cleavage enzyme | HEIDELBERG PHARMA AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-20030082167-A1 | Lapid cleavage enzyme | HEIDELBERG PHARMA HOLDING GMBH | 2003-05-01 | — | — | US | disclosed |
| US-20020106363-A1 | LIPID CLEAVAGE ENZYME | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2002-08-08 | — | — | US | disclosed |
| US-5277788-A | Twice-anodized aluminum article having an organo-phosphorus monolayer and process for making the article | ALUMINUM COMPANY OF AMERICA (US) | 1994-01-11 | — | — | US | disclosed |
| US-4163850-A | BACTERICIDES FOR WATER TREATMENT | PETROLITE CORPORATION (US) | 1979-08-07 | — | — | US | disclosed |
| US-4101654-A | BACTERIAL GROWTH INHIBITION | PETROLITE CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082167-A1 | Lapid cleavage enzyme | LAP3, NAALAD2, ENGASE | HDAC8 1303/4885MGAM 59/4885MAPT 3940/4885 |
| US-20020106363-A1 | LIPID CLEAVAGE ENZYME | SMPD1, MMEL1, ENGASE | HDAC8 1114/4885MGAM 45/4885MAPT 4749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.