SCHEMBL548518

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL548159	0.86	HNF4A (0.46)	PTPN1HNF4APTPN6AKR1C3AKR1C2
	SCHEMBL548758	0.84	ERN1 (0.50)	PTPN1HNF4APTPN6AKR1C3AKR1C2
	SCHEMBL29446584	0.83	PTPN1 (0.44)	PTPN1HNF4APTPN6AKR1C3AKR1C2
	SCHEMBL28715775	0.79	PTPN1 (0.55)	PTPN1HNF4APTPN6AKR1C3AKR1C2
	SCHEMBL28219794	0.79	BCAT2 (0.49)	PTPN1MEN1RAB9AKMT2AFOLH1
	SCHEMBL4840341	0.78	SMN1; SMN2 (0.51)	AKR1C3AKR1C2FABP3FABP4ALDH1A1
	SCHEMBL547717	0.78	HNF4A (0.45)	PTPN1HNF4APTPN6AKR1C3AKR1C2
	SCHEMBL28219796	0.77	BCAT2 (0.50)	MEN1RAB9AKMT2ABCAT2ERN1
	SCHEMBL5268526	0.76	HNF4A (0.59)	PTPN1HNF4APTPN6MEN1KMT2A
	SCHEMBL7772423	0.76	PTPN1 (0.59)	PTPN1HNF4APTPN6AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.