Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11047857 | 0.99 | HTR1A (0.71) | HTR1AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL3188003 | 0.93 | ALDH1A1 (0.71) | HTR1AALDH1A1DRD2KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL3196115 | 0.92 | HTR1A (0.71) | HTR1AALDH1A1DRD2KDM4ETDP1 | |
| SCHEMBL6956822 | 0.92 | KDM4E (0.72) | HTR1AALDH1A1DRD2KDM4ETDP1 | |
| SCHEMBL3160665 | 0.88 | HTR1A (0.79) | HTR1AALDH1A1MAPTHTTKMT2A | |
| Benzene SCHEMBL10433203 | 0.88 | HTR1A (0.79) | HTR1AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL11045002 | 0.87 | HTR1A (0.68) | HTR1AALDH1A1KMT2ADRD2KDM4E | |
| SCHEMBL4171472 | 0.86 | KDM4E (0.65) | HTR1AALDH1A1MAPTKMT2ADRD2 | |
| SCHEMBL3056156 | 0.86 | HTR1A (0.68) | HTR1AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL6352028 | 0.84 | HTR1A (1.00) | HTR1AALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185129-A1 | ACID ADDITION SALTS OF THIENOPYRANCARBOXAMIDE DERIVATIVES | RECORDATI IRELAND LIMITED (IE) | 2007-08-09 | — | — | US | disclosed |
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |
| CN-1136039-A | [3- (4-phenylpiperazin-1-yl) propylamino, thio and oxy ] -pyridine, pyrimidine and benzene derivatives | HOFFMANN LA ROCHE (CH) | 1996-11-20 | — | — | CN | disclosed |
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | disclosed |
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |
| US-3984555-A | HAVING HYPOTENSIVE, ANTIHISTAMINIC, AND ANALGESIC ACTIONS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185129-A1 | ACID ADDITION SALTS OF THIENOPYRANCARBOXAMIDE DERIVATIVES | CA2, SLC30A5, ASIC3 | HTR1A 2646/4885ALDH1A1 552/4885MAPT 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.