Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.68 |
| ▸ | HTR7 | P34969 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011780 | 0.88 | HTR1A (0.73) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL5485622 | 0.87 | HTR1A (0.73) | HTR1AHTR7DRD2DRD3ALDH1A1 | |
| SCHEMBL11630844 | 0.86 | HTR1A (0.67) | HTR1AHTR7DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11047857 | 0.86 | HTR1A (0.71) | HTR1AHTR7DRD2DRD3ALDH1A1 | |
| SCHEMBL6352115 | 0.85 | HTR1A (0.78) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL10545947 | 0.82 | DRD2 (0.66) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL9293656 | 0.82 | DRD2 (0.66) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL3188003 | 0.81 | ALDH1A1 (0.71) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL8828465 | 0.80 | DRD2 (0.64) | HTR1AHTR7DRD2DRD3DRD4 | |
| SCHEMBL3436467 | 0.80 | OPRM1 (0.55) | HTR1AHTR7DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |