Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.40 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486419 | 0.79 | CYP2C19 (0.58) | TP53ALOX15KDM4EALDH1A1NPC1 | |
| SCHEMBL5083468 | 0.70 | ALDH1A1 (0.65) | TP53TSHRALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28630199 | 0.70 | MLYCD (0.65) | MLYCDHSD17B10MAPK1TP53USP2 | |
| SCHEMBL5935115 | 0.69 | MLYCD (0.67) | MLYCDHSD17B10MAPK1TP53USP2 | |
| SCHEMBL4735448 | 0.68 | MAPK14 (0.55) | TP53TSHRALDH1A1HCAR3SMN1; SMN2 | |
| SCHEMBL22983342 | 0.68 | ALDH1A1 (0.65) | MLYCDHSD17B10TP53NPSR1KDM4E | |
| Water SCHEMBL11233247 | 0.68 | MLYCD (0.62) | MLYCDHSD17B10MAPK1TP53USP2 | |
| Water SCHEMBL11233238 | 0.68 | MLYCD (0.62) | MLYCDHSD17B10MAPK1TP53USP2 | |
| SCHEMBL789922 | 0.67 | ALDH1A1 (0.53) | HSD17B10TP53ALOX15KDM4EALDH1A1 | |
| SCHEMBL5486398 | 0.67 | CYP1A2 (0.46) | MAPK1TP53TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |