Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490900 | 0.78 | LMNA (0.41) | TAAR1 | |
| SCHEMBL6213929 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TAAR1HTR1DHDAC3HDAC1 | |
| SCHEMBL6217138 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TAAR1HTR1DHDAC3HDAC1 | |
| SCHEMBL9630715 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TAAR1HTR1DCYP1A2CYP2A6 | |
| SCHEMBL606472 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TAAR1HTR1DHDAC3HDAC1 | |
| SCHEMBL6404257 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TAAR1CYP1A2CYP2A6MAOA | |
| SCHEMBL14363072 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TAAR1HTR1DHDAC3HDAC1 | |
| SCHEMBL5482813 | 0.72 | GABRA1 (0.35) | ALDH1A1TAAR1CYP1A2 | |
| SCHEMBL10830808 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TAAR1HTR1DCYP1A2CYP2A6 | |
| SCHEMBL533804 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2A6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |