Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486140 | 0.84 | TAAR1 (0.46) | LMNATAAR1GAAAKR1B1SMN1; SMN2 | |
| SCHEMBL10013793 | 0.83 | LMNA (0.44) | LMNATAAR1P2RX7GAAPKM | |
| SCHEMBL5486671 | 0.78 | ALDH1A1 (0.43) | TAAR1 | |
| SCHEMBL9861759 | 0.76 | TAAR1 (0.43) | LMNATAAR1P2RX7GAAPKM | |
| SCHEMBL726569 | 0.76 | TAAR1 (0.43) | LMNATAAR1P2RX7PKMAKR1B1 | |
| SCHEMBL14363074 | 0.74 | IDO1 (0.43) | LMNATAAR1P2RX7GAAPKM | |
| SCHEMBL14127124 | 0.74 | TAAR1 (0.41) | LMNATAAR1P2RX7GAAPKM | |
| SCHEMBL1127909 | 0.74 | TAAR1 (0.52) | LMNATAAR1P2RX7GAAPKM | |
| SCHEMBL6358890 | 0.74 | TAAR1 (0.41) | LMNATAAR1P2RX7GAAPKM | |
| SCHEMBL14567074 | 0.74 | TAAR1 (0.41) | LMNATAAR1P2RX7GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |