Terephthalic Acid

Terephthalic Acid

SCHEMBL548684

O=C(O)c1ccc(C(=O)O)cc1.c1ccc2ccccc2c1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.72
DAO P14920 1/20 0.72
NAPRT Q6XQN6 1/20 0.72
TP53 P04637 1/20 0.71
SRD5A2 P31213 4/20 0.67
CES2 O00748 3/20 0.67
CES1 P23141 3/20 0.67
TRPA1 O75762 1/20 0.58
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL2463377 0.95 TSHR (0.65) TSHRDAONAPRTTP53SRD5A2
Naphthalene SCHEMBL11360560 0.94 TSHR (0.82) TSHRDAONAPRTTP53SRD5A2
Naphthalene SCHEMBL28954790 0.94 TSHR (0.82) TSHRDAONAPRTTP53SRD5A2
Naphthalene SCHEMBL498190 0.94 TSHR (0.82) TSHRDAONAPRTTP53SRD5A2
Terephthalic Acid SCHEMBL8944970 0.88 TSHR (0.64) TSHRDAONAPRTTP53SRD5A2
Terephthalic Acid SCHEMBL4961359 0.88 TSHR (0.93) TSHRDAONAPRTTP53SRD5A2
Terephthalic Acid SCHEMBL21443891 0.87 TSHR (0.92) TSHRDAONAPRTTP53SRD5A2
Beta-Naphtoic Acid SCHEMBL9008562 0.86 CES2 (0.65) TSHRDAONAPRTTP53SRD5A2
Naphthalene SCHEMBL6439633 0.85 CES2 (0.71) TSHRDAONAPRTTP53CES2
Benzoic Acid SCHEMBL975929 0.84 TSHR (1.00) TSHRDAONAPRTTP53SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180085862-A1 CONDUCTIVE POLYMER COMPOSITE AS PLASTIC SOLDER AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-03-29 US claimed
EP-2220276-B1 A NONWOVEN FOR AIR FILTRATION AND A PREPARATION METHOD THEREOF KOLON INC (KR) 2016-11-23 EP claimed
CN-105658430-A Delamination resistant heat shrinkable multilayer oxygen barrier film comprising polyester 克里奥瓦克公司 2016-06-08 CN claimed
CN-102791913-B Novel bicomponent fibers TREVIRA GMBH 2014-09-17 CN claimed
EP-2040936-B1 ORIENTED IMAGE COATING ON TRANSPARENT SUBSTRATE SICPA HOLDING SA (CH) 2014-06-04 EP claimed
US-8696031-B2 Oriented image coating on transparent substrate SICPA HOLDING SA (CH) 2014-04-15 US claimed
US-8496722-B2 Nonwoven for air filtration and a preparation method thereof KOLON INDUSTRIES, INC. (KR) 2013-07-30 US claimed
CN-102791913-A Novel bicomponent fibers TREVIRA GMBH 2012-11-21 CN claimed
EP-1713860-B1 METHOD OF MANUFACTURING CONTAINERS HAVING BARRIER PROPERTIES VALSPAR SOURCING INC (US) 2012-06-13 EP claimed
CN-101489803-B Security element with an oriented image coating on a transparent substrate, method for the production thereof, use thereof and security document SICPA HOLDING SA 2011-10-05 CN claimed
EP-2040936-A2 ORIENTED IMAGE COATING ON TRANSPARENT SUBSTRATE Sicpa Holding S.A. (CH) 2009-04-01 EP claimed
WO-2008009569-A2 ORIENTED IMAGE COATING ON TRANSPARENT SUBSTRATE SICPA HOLDING S.A. (CH) 2008-01-24 WO claimed
EP-1880866-A1 Oriented image coating on transparent substrate Sicpa Holding S.A. (CH) 2008-01-23 EP claimed
US-20070299182-A1 Polyester-Based Thermoplastic Composition, Manufacturing Process and Hollow Bodies Obtained From These Compositions CHIMIE, RHODIA (FR) 2007-12-27 US claimed
CN-1666888-A Optically variable security devices FLEX PRODUCTS INC (US) 2005-09-14 CN claimed
EP-1406942-A4 SOLUBLE SELF-ORIENTING MATEIALS AND CONDUCTIVE POLYMER COMPOSITIONS HAVING THE SAME PARA LTD (KR) 2005-02-02 EP claimed
EP-1406942-A1 SOLUBLE SELF-ORIENTING MATEIALS AND CONDUCTIVE POLYMER COMPOSITIONS HAVING THE SAME Para Limited (KR) 2004-04-14 EP claimed
WO-2002074833-A1 SOLUBLE SELF-ORIENTING MATEIALS AND CONDUCTIVE POLYMER COMPOSITIONS HAVING THE SAME PARA LIMITED (KR) 2002-09-26 WO claimed
US-5783631-A THERMOPLASTIC POLYMER PHASE AND CROSSLINKED RUBBER PHASE COMPRISING SELF-CURED BLEND OF TWO FUNCTIONALIZED ACRYLIC RUBBERS, FREE OF CURING AGENTS ADVANCED ELASTOMER SYSTEM, L.P. (US) 1998-07-21 US claimed
US-5523350-A TENSILE STRENGTH, ELONGATION, HEAT RESISTANCE ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1996-06-04 US claimed