Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990104 | 0.79 | MAOA (0.56) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL21758828 | 0.79 | MAOA (0.44) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL276675 | 0.77 | TDP1 (0.59) | MAPTLMNAMAPK1USP2ALDH1A1 | |
| SCHEMBL7855197 | 0.76 | MAOA (0.48) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL9655495 | 0.75 | F2 (0.38) | MAPTLMNAMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7986401 | 0.75 | MAOA (0.52) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL7984999 | 0.75 | MAOA (0.52) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL5818645 | 0.75 | MAOA (0.40) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL3383700 | 0.74 | NR4A2 (0.61) | MAOAMAOBMAPTLMNAMAPK1 | |
| SCHEMBL952229 | 0.73 | MAOA (0.50) | MAOAMAOBMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |