Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276675 | 0.77 | TDP1 (0.59) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL5487422 | 0.75 | MAOA (0.44) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL31374745 | 0.75 | F2 (0.46) | F2F10F12F7F3 | |
| Benzoic Acid SCHEMBL16764671 | 0.71 | TSHR (0.67) | PKMTDP1MAPTCES1KMT2A | |
| SCHEMBL13317140 | 0.71 | CES2 (0.52) | F2F10F12F7F3 | |
| SCHEMBL3661482 | 0.71 | L3MBTL1 (0.48) | F2F10F12F7F3 | |
| SCHEMBL10048780 | 0.71 | HDAC3 (0.57) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL2035615 | 0.69 | TDP1 (0.67) | TDP1L3MBTL1MAPTLMNANR4A2 | |
| SCHEMBL9886169 | 0.69 | GAA (0.40) | F2F10F12F7F3 | |
| SCHEMBL9425725 | 0.68 | PTGS2 (0.57) | F2F10F12F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254627-B1 | DERIVATIVES OF BENZHYDRYLOXYETHYLPIPERAZINE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1992-06-17 | — | — | EP | claimed |
| US-4908365-A | Pharmaceuticals | SOCIETE ANONYME (FR) | 1990-03-13 | — | — | US | disclosed |
| EP-0254627-A1 | Derivatives of benzhydryloxyethylpiperazine, processes for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-01-27 | — | — | EP | disclosed |