Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499408 | 0.76 | DDR2 (0.54) | NR3C1 | |
| SCHEMBL6689250 | 0.75 | ALDH1A1 (0.70) | SMN1; SMN2GAAKDM4EALDH1A1ESR2 | |
| SCHEMBL374497 | 0.73 | LTA4H (0.67) | SMN1; SMN2GAAKDM4EALDH1A1CA12 | |
| SCHEMBL30508414 | 0.73 | BMPR1B (0.64) | SMN1; SMN2GAAKDM4EALDH1A1ESR2 | |
| SCHEMBL29152375 | 0.73 | BMPR1B (0.64) | SMN1; SMN2GAAKDM4EALDH1A1ESR2 | |
| SCHEMBL4465091 | 0.72 | PRKAB2 (0.61) | SMN1; SMN2GAAKDM4EALDH1A1CA12 | |
| SCHEMBL30586324 | 0.72 | PRKAB2 (0.61) | SMN1; SMN2GAAKDM4EALDH1A1CA12 | |
| SCHEMBL5489767 | 0.72 | DHODH (0.41) | SMN1; SMN2NPC1MEN1KMT2AMAOA | |
| SCHEMBL14204158 | 0.72 | CA12 (0.65) | SMN1; SMN2GAAKDM4EALDH1A1CA12 | |
| Hydrochloric Acid SCHEMBL14742325 | 0.72 | NPC1 (0.68) | SMN1; SMN2GAAKDM4EALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |