Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494630 | 0.75 | ALDH1A1 (0.41) | CYP3A4HPGDTSHRHSD17B10MAPK1 | |
| SCHEMBL5490681 | 0.73 | — | — | |
| SCHEMBL5488906 | 0.73 | AR (0.35) | CYP3A4MAPK1AR | |
| SCHEMBL11699419 | 0.72 | CYP3A4 (0.53) | CYP3A4HPGDTSHRHSD17B10MAPK1 | |
| SCHEMBL18112469 | 0.70 | CYP3A4 (0.50) | CYP3A4HPGDTSHRHSD17B10MAPK1 | |
| SCHEMBL11323443 | 0.70 | CYP3A4 (0.50) | CYP3A4HPGDTSHRHSD17B10MAPK1 | |
| SCHEMBL28499177 | 0.68 | CYP3A4 (0.48) | CYP3A4HPGDTSHRHSD17B10MAPK1 | |
| SCHEMBL5488537 | 0.67 | SIRT1 (0.38) | CYP3A4CHRM1ALOX15TBXA2RADRA1A | |
| Pentachlorobenzene SCHEMBL11455164 | 0.66 | CYP3A4 (1.00) | CYP3A4HPGDTSHRHSD17B10MAPK1 | |
| Pentachlorobenzene SCHEMBL183144 | 0.66 | CYP3A4 (1.00) | CYP3A4HPGDTSHRHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |