Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.30 |
| ▸ | LCK | P06239 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.30 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488068 | 0.75 | CYP3A4 (0.46) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL5488906 | 0.72 | AR (0.35) | CYP3A4ARMAPK1 | |
| SCHEMBL29074259 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL5488098 | 0.70 | ALDH1A1 (0.33) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL1589735 | 0.69 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL1044618 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL320021 | 0.67 | TSHR (0.48) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL900267 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL2090996 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10CYP3A4RECQL | |
| SCHEMBL3028712 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |