SCHEMBL5488098

SCHEMBL5488098

Cc1c(Cl)cc(Cl)cc1C[Si](Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
HTT P42858 2/20 0.32
CRHR1 P34998 1/20 0.32
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
RECQL P46063 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PTGS2 P35354 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5490607 0.75
SCHEMBL5488095 0.71
SCHEMBL98117 0.71 ALDH1A1 (0.53) ALDH1A1MEN1LMNAPOLBHPGD
SCHEMBL5486729 0.71 ALDH1A1 (0.43) ALDH1A1LMNAHPGD
SCHEMBL7614522 0.71 CYP3A4 (0.43) ALDH1A1MEN1LMNAPOLBHPGD
SCHEMBL11564839 0.71 ALDH1A1 (0.33) ALDH1A1CYP3A4TSHRRECQLHSD17B10
SCHEMBL5494630 0.70 ALDH1A1 (0.41) ALDH1A1MEN1LMNAPOLBHPGD
SCHEMBL5488564 0.70 IDO1 (0.56) ALDH1A1LMNAHTTCYP3A4SMN1; SMN2
SCHEMBL28514732 0.69 ALDH1A1 (0.50) ALDH1A1MEN1LMNAPOLBHPGD
SCHEMBL5485036 0.68 CD44 (0.38) ALDH1A1LMNAPOLBCYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed