Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487167 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL1225414 | 0.68 | BACE1 (0.50) | ALDH1A1HPGDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL104109 | 0.67 | TP53 (0.44) | ALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL8142412 | 0.66 | TAAR1 (0.41) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| Biphenyl SCHEMBL21835012 | 0.65 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL2901415 | 0.65 | CYP4F2 (0.31) | MAPTNPSR1 | |
| SCHEMBL1963873 | 0.65 | IDO1 (0.42) | ALDH1A1HPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL6473234 | 0.65 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTNPSR1CYP1A2 | |
| SCHEMBL19809277 | 0.65 | HSPA5 (0.45) | KDM4E | |
| SCHEMBL29287974 | 0.64 | DHFR (0.41) | LMNAMAPTUSP7GCGRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |