Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 11/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493983 | 0.88 | PPARA (0.51) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5489203 | 0.83 | MAPT (0.41) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5487291 | 0.82 | RAB9A (0.46) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5488756 | 0.80 | MAPT (0.49) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5498824 | 0.79 | RAB9A (0.44) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5489330 | 0.78 | CCR2 (0.58) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5491138 | 0.77 | PYGL (0.52) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5491063 | 0.77 | CCR2 (0.60) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5493980 | 0.76 | RAB9A (0.44) | RAB9AMAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL5486853 | 0.76 | KCNH2 (0.44) | RAB9AMAPTSMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297696-B2 | Antagonists of MCP-1 function and methods of use thereof | TELIK, INC. (US) | 2007-11-20 | — | — | US | claimed |