Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487291 | 0.79 | RAB9A (0.46) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5489330 | 0.77 | CCR2 (0.58) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5488744 | 0.76 | RAB9A (0.46) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5486853 | 0.76 | KCNH2 (0.44) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5493983 | 0.76 | PPARA (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5498824 | 0.76 | RAB9A (0.44) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5491138 | 0.75 | PYGL (0.52) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5488756 | 0.75 | MAPT (0.49) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5491063 | 0.75 | CCR2 (0.60) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL5496386 | 0.73 | ACLY (0.52) | RAB9ANPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297696-B2 | Antagonists of MCP-1 function and methods of use thereof | TELIK, INC. (US) | 2007-11-20 | — | — | US | claimed |