SCHEMBL548909

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL549204	0.88	LPAR1 (0.45)	MEN1KMT2ATDP1MMP13LPAR1
	SCHEMBL549070	0.78	RORC (0.44)	MEN1KMT2AMLYCDMMP13
	SCHEMBL2922162	0.72	LPAR1 (0.41)	TDP1LPAR1LPAR5
	SCHEMBL6989792	0.70	MEN1 (0.45)	MEN1NPC1RAB9AKMT2ATDP1
	SCHEMBL6488874	0.68	MMP13 (0.53)	MEN1KMT2ATDP1MMP13
	SCHEMBL12415941	0.66	TERT (0.40)	MMP13
	SCHEMBL23361722	0.65	POLB (0.52)	RAB9AKMT2ATDP1MMP13
	SCHEMBL6488871	0.65	CFTR (0.49)	MEN1KMT2ATDP1MMP13
	SCHEMBL6235516	0.64	KDM4C (0.49)	MEN1KMT2AMMP13LPAR1LPAR5
	SCHEMBL3655141	0.63	KMT2A (0.50)	MEN1NPC1RAB9AKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.