SCHEMBL5489461

SCHEMBL5489461

C=CCC1CC(=O)N(CC=C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.39
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 1/20 0.38
NOS1 P29475 2/20 0.35
NOS2 P35228 2/20 0.35
CYP3A4 P08684 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP19A1 P11511 1/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CASP3 P42574 1/20 0.32
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22215826 0.86 L3MBTL1 (0.37) FAAHALDH1A1L3MBTL1MAPTCYP3A4
SCHEMBL22215824 0.81 ALDH1A1 (0.36) FAAHALDH1A1L3MBTL1MAPTMEN1
SCHEMBL22215817 0.79 ALDH1A1 (0.42) ALDH1A1L3MBTL1MAPTCYP3A4MEN1
SCHEMBL22215828 0.78 L3MBTL1 (0.36) ALDH1A1L3MBTL1MAPTMEN1KMT2A
SCHEMBL26361690 0.78 ALDH1A1 (0.48) FAAHALDH1A1L3MBTL1MAPTMEN1
SCHEMBL22215815 0.77 TSHR (0.50) FAAHALDH1A1CYP19A1TSHR
SCHEMBL8517673 0.77 ALDH1A1 (0.41) ALDH1A1L3MBTL1MAPTCYP3A4MEN1
SCHEMBL8517676 0.76 MAPT (0.46) ALDH1A1L3MBTL1MAPTCYP3A4MEN1
SCHEMBL7077014 0.76 ALDH1A1 (0.40) ALDH1A1L3MBTL1MAPTCYP3A4MEN1
SCHEMBL2205249 0.76 FAAH (0.44) FAAHALDH1A1NOS1NOS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
WO-2020145111-A1 THIOL COMPOUND, METHOD FOR SYNTHESIZING SAME, AND USES FOR SAID THIOL COMPOUND 四国化成工業株式会社 2020-07-16 WO disclosed
US-20190177651-A1 LUBRICANT COMPOSITIONS COMPRISING OLEFIN COPOLYMER DISPERSANTS IN COMBINATION WITH ADDITIVES AFTON CHEMICAL CORPORATION 2019-06-13 US disclosed
US-20160201001-A1 ADDITIVE FOR OIL-BASED LUBRICANTS HAVING IMPROVED EXTREME PRESSURE PROPERTIES Terralub GmbH (DE) 2016-07-14 US disclosed
WO-2014003162-A1 LUBRICANT COMPOSITION 出光興産株式会社 (JP) 2014-01-03 WO disclosed
US-20070071701-A1 Antiperspirant actives and compositions Outdoor Wireless Networks LLC 2007-03-29 US disclosed
EP-1643963-A1 ANTIPERSPIRANT ACTIVES AND COMPOSITIONS Unilever Plc (GB) 2006-04-12 EP disclosed
US-20040265254-A1 Antiperspirant or deodorant composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-12-30 US disclosed
EP-1476126-A1 ANTIPERSPIRANT OR DEODORANT COMPOSITION UNILEVER PLC (GB) 2004-11-17 EP disclosed
US-4855378-A ADHESION PROMOTERS WACKER-CHEMIE GMBH (DE) 1989-08-08 US disclosed
EP-0270710-A1 Production of lubricating oil dispersant TEXACO DEVELOPMENT CORPORATION (US) 1988-06-15 EP disclosed
US-4713189-A MANNICH REACTION PRODUCT OF A POLYAMINE, A PHENOL AND AN ALDEHYDE TEXACO, INC. (US) 1987-12-15 US disclosed
US-4713191-A Diiscyanate acid lubricating oil dispersant and viton seal additives TEXACO INC. (US) 1987-12-15 US disclosed
US-4699724-A Post-coupled mono-succinimide lubricating oil dispersant and viton seal additives TEXACO INC. (US) 1987-10-13 US disclosed
US-4663064-A PARTIALLY GLYCOLATED POLYISOBUTYLENE SUCCINIMIDES COUPLED WITH DIACID TEXACO INC. (US) 1987-05-05 US disclosed
US-4636322-A OIL ADDITIVES TEXACO INC. (US) 1987-01-13 US disclosed
EP-0119675-B1 HYDROCARBYL-SUBSTITUTED MONO AND BIS SUCCINIMIDE HAVING POLYAMINE CHAIN LINKED HYDROXYACYL RADICALS AND MINERAL OIL COMPOSITIONS CONTAINING SAME TEXACO DEVELOPMENT CORPORATION (US) 1986-10-29 EP disclosed
US-4482464-A Hydrocarbyl-substituted mono- and bis-succinimide having polyamine chain linked hydroxyacyl radicals and mineral oil compositions containing same TEXACO INC. (US) 1984-11-13 US disclosed
EP-0119675-A1 Hydrocarbyl-substituted mono and bis succinimide having polyamine chain linked hydroxyacyl radicals and mineral oil compositions containing same TEXACO DEVELOPMENT CORPORATION (US) 1984-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound TST, TMT1A, CTH FAAH 1703/4885ALDH1A1 412/4885L3MBTL1 2932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.