Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489767 | 0.80 | DHODH (0.41) | SMN1; SMN2NPC1NFKB1NFKB2RELA | |
| SCHEMBL25325847 | 0.80 | OPRK1 (0.47) | MAPTGAAKDM4EALDH1A1HPGD | |
| SCHEMBL5492755 | 0.79 | MAPT (0.50) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL5487922 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ACYP1A2KMT2A | |
| SCHEMBL28707488 | 0.75 | KMT2A (0.54) | MAPTSMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL2328573 | 0.74 | KDM4E (0.53) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL2324851 | 0.71 | KMT2A (0.55) | MAPTLMNACYP2C9CYP2C19KMT2A | |
| SCHEMBL24364823 | 0.71 | NNMT (0.43) | KMT2ATDP1KDM4E | |
| SCHEMBL5592985 | 0.71 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL4728295 | 0.71 | KMT2A (0.50) | MAPTSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |