Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31674346 | 1.00 | NPSR1 (0.56) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL11325941 | 0.95 | NPSR1 (0.60) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL11747281 | 0.91 | NPSR1 (0.56) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL3877692 | 0.86 | ALOX15 (0.58) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL3873579 | 0.86 | ALOX15 (0.58) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL3876079 | 0.86 | ALOX15 (0.58) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL16527228 | 0.84 | ALOX15 (0.50) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL19999155 | 0.84 | ALOX15 (0.55) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL23286929 | 0.83 | NPSR1 (0.48) | NPSR1ALOX15RXRARXRBRXRG | |
| SCHEMBL3278996 | 0.83 | ALDH1A1 (0.57) | NPSR1ALOX15RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | claimed |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-18 | — | — | US | claimed |
| EP-1494987-A1 | METHOD FOR THE PRODUCTION OF 2,4,5-TRIMETHYLPHENYL ACETIC ACID | Bayer CropScience AG (DE) | 2005-01-12 | — | — | EP | claimed |
| WO-2003084914-A1 | METHOD FOR THE PRODUCTION OF 2,4,5-TRIMETHYLPHENYL ACETIC ACID | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-10-16 | — | — | WO | claimed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| CN-1659129-A | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-24 | — | — | CN | disclosed |
| CN-1659129-A | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-24 | — | — | CN | disclosed |
| WO-2003084914-A1 | METHOD FOR THE PRODUCTION OF 2,4,5-TRIMETHYLPHENYL ACETIC ACID | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-10-16 | — | — | WO | disclosed |
| WO-2003084914-A1 | METHOD FOR THE PRODUCTION OF 2,4,5-TRIMETHYLPHENYL ACETIC ACID | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-10-16 | — | — | WO | disclosed |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | LIEB FOLKER (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6511942-B1 | Animal husbandry, veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-28 | — | — | US | disclosed |
| EP-0837847-B1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6110872-A | 3-(2,4,5-TRISUBSTITUTED PHENYL), 4-HYDROXY,5,5-(CYCLOALKYL OR HETEROCYCLOALKYL)PYRROLIN-2-ONE AND DERIVATIVES; METHOD OF MAKING BY INTRAMOLECULAR CONDENSATION OF SPECIFIED COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |
| EP-0837847-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001535-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | CA6, DDC, HACL2 | NPSR1 4120/4885ALOX15 4422/4885RXRA 4152/4885 |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, HPD | NPSR1 3011/4885ALOX15 684/4885RXRA 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.