SCHEMBL549076

SCHEMBL549076

FC(F)(F)CNc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAPT P10636 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.46
PTPN1 P18031 1/20 0.40
PTPRZ1 P23471 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CTSD P07339 1/20 0.39
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
MAPK1 P28482 1/20 0.38
PTGS2 P35354 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15114128 0.81 MAPT (0.50) ALDH1A1MAPTL3MBTL1PTPN1PTPRZ1
SCHEMBL13985100 0.79 NPC1 (0.59) PTPN1TDP1
SCHEMBL3953252 0.78 ALDH1A1 (0.58) ALDH1A1MAPTL3MBTL1PTPN1PTPRZ1
SCHEMBL11556501 0.78 AR (0.39) ALDH1A1MAPTAR
SCHEMBL17501646 0.78 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1PTPN1PTPRZ1
SCHEMBL15114122 0.78 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1PTPN1PTPRZ1
SCHEMBL15456013 0.76 AR (0.35) ALDH1A1MAPTAR
SCHEMBL924303 0.76 KIF11 (0.47) MAPTCA12CA2AR
SCHEMBL18235918 0.76 CTSD (0.44) L3MBTL1CTSDAR
SCHEMBL10426372 0.76 SMN1; SMN2 (0.44) ALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004528205-A 2004-09-16 JP claimed
EP-1389225-A2 METHOD FOR BONDING A FLUOROPOLYMER TO A SUBSTRATE AND COMPOSITE ARTICLE RESULTING THEREFROM 3M Innovative Properties Company (US) 2004-02-18 EP claimed
US-20030077454-A1 Fluoropolymer bonding composition and method 3M INNOVATIVE PROPERTIES COMPANY 2003-04-24 US claimed
WO-2002094914-A2 METHOD FOR BONDING A FLUOROPOLYMER TO A SUBSTRATE AND COMPOSITE ARTICLE RESULTING THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-11-28 WO claimed
EP-4692072-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
WO-2024202087-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2024-10-03 WO disclosed
US-20240025919-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF GENENTECH, INC. 2024-01-25 US disclosed
US-11874601-B2 Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent TOKYO OHKA KOGYO CO., LTD. (JP) 2024-01-16 US disclosed
US-11835857-B2 Resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-12-05 US disclosed
US-11829068-B2 Resist composition, method of forming resist pattern, compound, and resin TOKYO OHKA KOGYO CO., LTD. (JP) 2023-11-28 US disclosed
US-11822240-B2 Resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-11-21 US disclosed
US-11780946-B2 Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-10 US disclosed
EP-0171205-A1 Fluoroalkylaryliodonium compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-02-12 EP disclosed
EP-0049555-B1 2-TRIFLUOROMETHYL-4-HYDROXY-3 QUINOLINE-CARBOXYLIC-ACID DERIVATIVES AND THEIR PREPARATION ROUSSEL-UCLAF (FR) 1984-02-22 EP disclosed
US-4285696-A CATIONIC FIBER-REACTIVE DYES FOR DYEING FIBERS OF POLYESTERS, POLYAMIDES, AND POLYMERS OF ACRYLONITRILE P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1981-08-25 US disclosed
US-4146625-A QUINOLONECARBOXYLIC ACIDS FOR CONTROL OF BACTERIAL DISEASES IN PLANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-03-27 US disclosed
US-4116954-A 5-[4-(N-trifluoroethyl-amino)phenylazo]-pyrazolium dyestuffs PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-09-26 US disclosed
US-4059626-A Trifluoroethylanilines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-11-22 US disclosed
US-4059626-A Trifluoroethylanilines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-11-22 US disclosed
US-4036962-A BACTERICIDES E. I. DU PONT DE NEMOURS AND CO. (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11874601-B2 Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent MRPS23, MRPS22, SLC11A2 ALDH1A1 2173/4885MAPT 4792/4885L3MBTL1 2206/4885
US-20240025919-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF AZI2, TET3, OXA1L ALDH1A1 1000/4885MAPT 3374/4885L3MBTL1 4021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.