Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490900 | 0.84 | LMNA (0.41) | TAAR1AKR1B1SMN1; SMN2LMNAGAA | |
| SCHEMBL5488906 | 0.82 | AR (0.35) | TAAR1CYP2A6PNMT | |
| SCHEMBL5494630 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2CYP1A2LMNATSHRALDH1A1 | |
| SCHEMBL5486703 | 0.72 | IDO1 (0.52) | TAAR1SMN1; SMN2CYP1A2LMNATSHR | |
| SCHEMBL3333154 | 0.71 | TAAR1 (0.55) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL673238 | 0.71 | TAAR1 (0.70) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| Iodide SCHEMBL28327974 | 0.70 | TAAR1 (0.48) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL1438087 | 0.70 | TAAR1 (0.48) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL5486729 | 0.70 | ALDH1A1 (0.43) | TAAR1LMNAALDH1A1PNMT | |
| SCHEMBL1007397 | 0.69 | TAAR1 (0.52) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |