SCHEMBL5491165

SCHEMBL5491165

C=Cc1ccc(N(c2ccc(C(C)(C)C)cc2)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
CYP1A2 P05177 1/20 0.40
TSHR P16473 3/20 0.38
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
LMNA P02545 2/20 0.37
TYR P14679 1/20 0.37
AMY1A P0DUB6 1/20 0.36
PKM P14618 1/20 0.36
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HDAC8 Q9BY41 1/20 0.34
CA2 P00918 2/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5397905 0.94 KIF11 (0.41) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
SCHEMBL17849333 0.94 KIF11 (0.41) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
SCHEMBL14292454 0.88 ALDH1A1 (0.38) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
SCHEMBL15198 0.87 ALDH1A1 (0.58) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
SCHEMBL14293252 0.87 CYP1A2 (0.36) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
SCHEMBL14292451 0.86 RAB9A (0.44) ALDH1A1CYP1A2CA2MAPTCA1
Hydrogen Sulfide SCHEMBL29029008 0.85 ALDH1A1 (0.55) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
Ethylene SCHEMBL28319400 0.85 ALDH1A1 (0.55) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
Methane SCHEMBL27697370 0.85 ALDH1A1 (0.55) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B
Ammonia Solution, Strong SCHEMBL28148721 0.85 ALDH1A1 (0.55) ALDH1A1CYP1A2TSHRGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276627-B2 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2007-10-02 US claimed
US-20060224017-A1 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2006-10-05 US claimed
EP-3621945-B1 STILBENE DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS AMBIENT PHOTONICS INC (US) 2025-12-10 EP disclosed
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2024-06-25 US disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 US disclosed
US-11286233-B2 Stilbene derivatives for the treatment of CNS and other disorders Ambient Photonics, Inc. (US) 2022-03-29 US disclosed
US-11286233-B2 Stilbene derivatives for the treatment of CNS and other disorders Ambient Photonics, Inc. (US) 2022-03-29 US disclosed
US-20210114976-A1 Stilbene Derivatives for the Treatment of CNS and Other Disorders Ambient Photonics, Inc. (US) 2021-04-22 US disclosed
US-20210114976-A1 Stilbene Derivatives for the Treatment of CNS and Other Disorders Ambient Photonics, Inc. (US) 2021-04-22 US disclosed
US-20210082632-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2021-03-18 US disclosed
US-20210082632-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2021-03-18 US disclosed
WO-2013098113-A2 CROSSLINKABLE COMPOSITIONS COMPRISING ADDITION POLYMERIZABLE GROUPS SOLVAY SA (BE) 2013-07-04 WO disclosed
US-7276627-B2 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2007-10-02 US disclosed
US-20060224017-A1 One pot sequential reactions and novel products produced thereby IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060224017-A1 One pot sequential reactions and novel products produced thereby PNMT, CYP1A1, TERT ALDH1A1 602/4885CYP1A2 26/4885TSHR 3843/4885
US-20210114976-A1 Stilbene Derivatives for the Treatment of CNS and Other Disorders CLN6, MAPT, PSEN2 ALDH1A1 2357/4885CYP1A2 4384/4885TSHR 3202/4885
US-11286233-B2 Stilbene derivatives for the treatment of CNS and other disorders CLN6, MAPT, PSEN2 ALDH1A1 2357/4885CYP1A2 4384/4885TSHR 3202/4885
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes FDFT1, SUN2, CDC73 ALDH1A1 352/4885CYP1A2 2358/4885TSHR 4325/4885
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes FDFT1, SUN2, CDC73 ALDH1A1 352/4885CYP1A2 2358/4885TSHR 4325/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 ALDH1A1 406/4885CYP1A2 1760/4885TSHR 4465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.