Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103406 | 0.76 | ALDH1A1 (0.33) | CYP2C19SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL1683176 | 0.70 | CA12 (0.42) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL424239 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL9865734 | 0.66 | KDM4E (0.50) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL2171152 | 0.64 | HRH1 (0.45) | CYP2C19SMN1; SMN2CYP1A2CYP2D6NPSR1 | |
| SCHEMBL8489804 | 0.64 | CCR5 (0.41) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 | |
| SCHEMBL11124263 | 0.64 | TSHR (0.38) | CYP2C19SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL11124275 | 0.64 | TSHR (0.38) | CYP2C19SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL6827277 | 0.62 | CYP2C19 (0.47) | CYP2C19SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL9572737 | 0.61 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP1A2CYP2D6PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247738-B2 | Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl) ethoxycarbonyl]-5-oxazolidine carboxylic acids | DABUR INDIA LIMITED (IN) | 2007-07-24 | — | — | US | disclosed |