SCHEMBL5493527

SCHEMBL5493527

CC(Cc1ccccc1)[Si](Cl)(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.52
TAAR1 Q96RJ0 5/20 0.52
SLC6A2 P23975 3/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
MAOA P21397 1/20 0.52
CYP2A6 P11509 1/20 0.52
ADORA2A P29274 1/20 0.52
ADORA1 P30542 1/20 0.52
SLC18A2 Q05940 1/20 0.48
CYP2D6 P10635 1/20 0.48
TRPA1 O75762 2/20 0.47
EPHX1 P07099 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
HTR2A P28223 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRK1 P41145 1/20 0.44
KCNH2 Q12809 1/20 0.44
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8759204 0.84 SIGMAR1 (0.50) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL8714924 0.84 SIGMAR1 (0.50) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL2772048 0.79 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL28677694 0.76 SIGMAR1 (0.50) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL1504696 0.74 EPHX1 (0.46) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL10696904 0.74 SIGMAR1 (0.48) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL8759229 0.74 SIGMAR1 (0.48) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL66064 0.73 SIGMAR1 (0.58) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL9863446 0.73 TAAR1 (0.58) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL2098592 0.73 SIGMAR1 (0.52) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102786837-B Uv-curing type ink jet compositions and printed article 精工爱普生株式会社 2016-12-07 CN disclosed
CN-105965881-A Three-dimensional modeling apparatus and three-dimensional object manufacturing method 精工爱普生株式会社 2016-09-28 CN disclosed
CN-103242702-B Uv-curing type ink jet compositions and record thing 精工爱普生株式会社 2016-07-13 CN disclosed
CN-104924609-A Apparatus for producing three-dimensional structure, three-dimensional structure and method of producing three-dimensional structure SEIKO EPSON CORP 2015-09-23 CN disclosed
CN-104908318-A Manufacturing method of three-dimensional structure, three-dimensional structure manufacturing apparatus, and three-dimensional structure SEIKO EPSON CORP 2015-09-16 CN disclosed
CN-104908317-A Three-dimensional structure manufacturing apparatus, manufacturing method of three-dimensional structure, and three-dimensional structure SEIKO EPSON CORP 2015-09-16 CN disclosed
CN-104859146-A Three dimensional mold object manufacturing apparatus, method for manufacturing three dimensional mold object, and three dimensional mold object SEIKO EPSON CORP 2015-08-26 CN disclosed
CN-104842555-A Apparatus for manufacturing three-dimensional shaped object, method of manufacturing three-dimensional shaped object, and three-dimensional shaped object SEIKO EPSON CORP 2015-08-19 CN disclosed
CN-104647754-A Three-dimensional shaped object, three-dimensional shaped object manufacturing method and apparatus, method of controlling three-dimensional shaped object manufacturing apparatus, and program for controlling three-dimensional shaped object manufacturing apparatus SEIKO EPSON CORP 2015-05-27 CN disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
EP-1244676-B1 SULFUR-CONTAINING SILANE AS COUPLING AGENTS GEN ELECTRIC (US) 2004-10-13 EP disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed
US-6518335-B2 Made by chlorine-free process by reacting alkoxysilane acetals such as (3,3-dimethoxypropyl)trimethoxysilane with sulfurating agents such as sulfur, hydrogen sulfide, or thiols; use in silica-filled rubbers CROMPTON CORPORATION 2003-02-11 US disclosed
CN-1394208-A Sulfur-containing silane coupling agents CROMPTON CORP (US) 2003-01-29 CN disclosed
EP-1244676-A1 SULFUR-CONTAINING SILANE AS COUPLING AGENTS Crompton Corporation (US) 2002-10-02 EP disclosed
US-20020002220-A1 SULFUR-CONTAINING SILANE COUPLING AGENTS MOMENTIVE PERFORMANCE MATERIALS INC. 2002-01-03 US disclosed
WO-2001049695-A1 SULFUR-CONTAINING SILANE AS COUPLING AGENTS CROMPTON CORPORATION (US) 2001-07-12 WO disclosed