Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497635 | 0.81 | POLB (0.40) | GABRA1GABRG2GABRB3KIF11RXRA | |
| SCHEMBL30192521 | 0.75 | AKR1C3 (0.44) | GABRA1GABRG2GABRB3KIF11PDK2 | |
| SCHEMBL7797061 | 0.75 | AKR1C3 (0.44) | GABRA1GABRG2GABRB3KIF11PDK2 | |
| SCHEMBL2380170 | 0.74 | KIF11 (0.51) | KIF11TPMTRXRARXRBRXRG | |
| SCHEMBL2771570 | 0.72 | CES2 (0.52) | TPMTRXRARXRBRXRG | |
| SCHEMBL31133402 | 0.72 | CES2 (0.52) | TPMTRXRARXRBRXRG | |
| SCHEMBL22587376 | 0.70 | GABRB3 (0.50) | GABRA1GABRG2GABRB3KIF11 | |
| SCHEMBL422824 | 0.70 | TPMT (0.59) | TPMTALOX15TSHRHIF1ACA12 | |
| SCHEMBL1951073 | 0.70 | TPMT (0.59) | TPMTALOX15TSHRHIF1ACA12 | |
| SCHEMBL3658322 | 0.69 | DHODH (0.44) | KIF11RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161542-A1 | Ptb1b photoprobes | RAMACHANDRAN CHIDAMBARAM | 2007-07-12 | — | — | US | disclosed |
| WO-2005056582-A1 | PTP1B PHOTOPROBES | MERCK FROSST CANADA LTD. (CA) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161542-A1 | Ptb1b photoprobes | PTBP1, PTBP3, PPP1R1B | GABRA1 2397/4885GABRG2 2486/4885GABRB3 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.