Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 4/20 | 0.40 |
| ▸ | NMT2 | O60551 | 3/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405576 | 0.94 | SLC6A5 (0.48) | GSRSLC6A5FOLH1NMT1NMT2 | |
| SCHEMBL8013202 | 0.88 | LMNA (0.57) | GSRSLC6A5FOLH1NMT1NMT2 | |
| SCHEMBL7215943 | 0.86 | SLC6A5 (0.59) | SLC6A5KMT2ADNM1GNAI3GNAO1 | |
| SCHEMBL7209829 | 0.86 | SLC6A5 (0.59) | SLC6A5KMT2ADNM1GNAI3GNAO1 | |
| SCHEMBL7215978 | 0.86 | SLC6A5 (0.59) | SLC6A5KMT2ADNM1GNAI3GNAO1 | |
| SCHEMBL2363939 | 0.85 | CYP2D6 (0.55) | GSRSLC6A5FOLH1NMT1NMT2 | |
| SCHEMBL5494287 | 0.78 | GSR (0.34) | GSRSLC6A5FOLH1NMT1NMT2 | |
| SCHEMBL9442358 | 0.78 | GSR (0.47) | GSRSLC6A5FOLH1RNPEPLMNA | |
| SCHEMBL2679022 | 0.78 | GSR (0.52) | GSRSLC6A5FOLH1RNPEPLMNA | |
| SCHEMBL232587 | 0.77 | SLC6A5 (0.65) | GSRSLC6A5FOLH1NMT1NMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159292-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | Administrators of The Tulane Educational Fund (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000009537-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2000-02-24 | — | — | WO | claimed |
| US-7250399-B2 | Compounds having growth hormone releasing activity | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2007-07-31 | — | — | US | disclosed |
| US-6468974-B1 | OLIGOPEPTIDES THAT PROVIDE DESIRABLE IN VITRO AND IN VIVO GROWTH HORMONE RELEASING ACTIVITY AND HAVE AT LEAST ONE OTHER DESIRABLE BIOLOGICAL ACTIVITY SUCH AS INCREASED RETENTION TIME | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | 2002-10-22 | — | — | US | disclosed |
| US-20020151501-A1 | Compounds having growth hormone releasing activity | BOWERS CYRIL Y (US) | 2002-10-17 | — | — | US | disclosed |
| EP-1159292-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | Administrators of The Tulane Educational Fund (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000009537-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151501-A1 | Compounds having growth hormone releasing activity | GHSR, GHRHR, NPY1R | GSR 3429/4885SLC6A5 4169/4885FOLH1 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.