Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438029 | 0.77 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL27635068 | 0.72 | GABRA5 (0.52) | LMNAMEN1KMT2APIN1 | |
| SCHEMBL6315068 | 0.71 | OPRM1 (0.40) | ALDH1A1SLC6A4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5914841 | 0.71 | GRM6 (0.35) | ALDH1A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL6401268 | 0.71 | OPRM1 (0.40) | ALDH1A1SLC6A4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10969254 | 0.71 | KDM4E (0.39) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5711476 | 0.71 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL6315318 | 0.70 | THRB (0.34) | ALDH1A1RAB9ANPC1SMN1; SMN2PIN1 | |
| SCHEMBL5914861 | 0.70 | THRB (0.34) | ALDH1A1RAB9ANPC1SMN1; SMN2PIN1 | |
| SCHEMBL6328828 | 0.69 | DGAT1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656360-B1 | THIAZOLINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2007-08-15 | — | — | EP | disclosed |
| EP-1656360-A1 | THIAZOLINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-17 | — | — | EP | disclosed |
| US-20050014952-A1 | Novel thiazoline derivatives as selective androgen receptor modulators (SARMS) | JASSEN PHARMACEUTICA N.V. (BE) | 2005-01-20 | — | — | US | disclosed |
| WO-2004113309-A1 | THIAZOLINE DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014952-A1 | Novel thiazoline derivatives as selective androgen receptor modulators (SARMS) | AR, NR5A1, NR5A2 | ALDH1A1 512/4885PKM 253/4885SLC6A4 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.