Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858027 | 0.90 | HTR1A (0.67) | HTR1APOLBALDH1A1KDM4ELMNA | |
| SCHEMBL12928358 | 0.87 | HTR1A (0.69) | HTR1APOLBALDH1A1KDM4ELMNA | |
| SCHEMBL22350718 | 0.83 | HTR1A (0.69) | HTR1APOLBALDH1A1KDM4ELMNA | |
| SCHEMBL196372 | 0.81 | HTR1A (0.43) | HTR1APOLBALDH1A1KDM4ELMNA | |
| Alanine SCHEMBL28004622 | 0.78 | HTR1A (0.53) | HTR1APOLBALDH1A1KDM4ELMNA | |
| SCHEMBL18918295 | 0.78 | HTR1A (0.49) | HTR1APOLBALDH1A1KDM4ELMNA | |
| Alanine SCHEMBL27702084 | 0.76 | HTR1A (0.55) | HTR1APOLBALDH1A1KDM4ELMNA | |
| SCHEMBL2160334 | 0.75 | HTR1A (0.52) | HTR1APOLBALDH1A1KDM4ELMNA | |
| SCHEMBL29626142 | 0.75 | HTR1A (0.44) | HTR1APOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL15904342 | 0.75 | HRH3 (0.41) | ALDH1A1MAPTTSHRKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513814-A4 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO (JP) | 2007-03-14 | — | — | EP | disclosed |
| EP-1513814-A1 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099787-A1 | NOVEL PIPERIDINE COMPOUND | TANABE SEIYAKU CO., LTD. (JP) | 2003-12-04 | — | — | WO | disclosed |