Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196372 | 0.90 | HTR1A (0.43) | HTR1APOLBALDH1A1KDM4EMAPT | |
| SCHEMBL5495402 | 0.75 | HTR1A (0.55) | HTR1APOLBALDH1A1KDM4EMAPT | |
| Diethylcarbamazine SCHEMBL1819685 | 0.69 | HTR1A (1.00) | HTR1APOLBALDH1A1KDM4EMAPT | |
| Diethylcarbamazine SCHEMBL67289 | 0.69 | HTR1A (1.00) | HTR1APOLBALDH1A1KDM4EMAPT | |
| SCHEMBL11506548 | 0.67 | HTR1A (0.74) | HTR1APOLBALDH1A1KDM4EMAPT | |
| SCHEMBL11508763 | 0.67 | HTR1A (0.68) | HTR1APOLBALDH1A1KDM4EMAPT | |
| Diethylcarbamazine SCHEMBL10412471 | 0.67 | HTR1A (0.96) | HTR1APOLBALDH1A1KDM4EMAPT | |
| SCHEMBL9015335 | 0.67 | — | — | |
| SCHEMBL5908857 | 0.67 | SMN1; SMN2 (0.47) | MAPTTSHR | |
| SCHEMBL12928358 | 0.67 | HTR1A (0.69) | HTR1APOLBALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631006-B1 | Ink jet printing method and print medium for use in the method | CANON KK (JP) | 1998-01-14 | — | — | EP | claimed |
| US-5515093-A | Ink jet printing method and print medium for use in the method | CANON KABUSHIKI KAISHA (JP) | 1996-05-07 | — | — | US | claimed |
| EP-0631006-A1 | Ink jet printing method and print medium for use in the method | CANON KABUSHIKI KAISHA (JP) | 1994-12-28 | — | — | EP | claimed |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | SYMRISE AG (DE) | 2024-01-04 | — | — | US | disclosed |
| EP-4247791-A2 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2023-09-27 | — | — | EP | disclosed |
| WO-2023144326-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023143741-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-08-03 | — | — | WO | disclosed |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-06-18 | — | — | US | disclosed |
| US-10584134-B2 | Use of physiological cooling active ingredients, and agents containing such active ingredients | SYMRISE AG (DE) | 2020-03-10 | — | — | US | disclosed |
| US-10398159-B2 | Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof | BASF SE (DE) | 2019-09-03 | — | — | US | disclosed |
| US-20180093997-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2018-04-05 | — | — | US | disclosed |
| US-8506748-B2 | Imaging process for flooring material | Octi Tech Limited, LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120263659-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2012-10-18 | — | — | US | disclosed |
| US-20110180202-A1 | IMAGING PROCESS FOR FLOORING MATERIAL | Octi Tech Limited, LLC (US) | 2011-07-28 | — | — | US | disclosed |
| WO-2011091266-A2 | IMAGING PROCESS FOR FLOORING MATERIAL | Octi Tech Limited, LLC (US) | 2011-07-28 | — | — | WO | disclosed |
| US-5922625-A | Print medium for use in ink jet printing method | CANON KABUSHIKI KAISHA (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0631006-B1 | Ink jet printing method and print medium for use in the method | CANON KK (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-5515093-A | Ink jet printing method and print medium for use in the method | CANON KABUSHIKI KAISHA (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0631006-A1 | Ink jet printing method and print medium for use in the method | CANON KABUSHIKI KAISHA (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-4254217-A | A DIMETHYLOL ETHYLENE UREA COMPOUND | MITSUBISHI PAPER MILLS, LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | TTPA, TREH, TAS2R45 | HTR1A 2629/4885POLB 3674/4885ALDH1A1 1658/4885 |
| US-10398159-B2 | Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof | TRPM8, TRPM7, TRPM2 | HTR1A 510/4885POLB 4624/4885ALDH1A1 3977/4885 |
| US-10584134-B2 | Use of physiological cooling active ingredients, and agents containing such active ingredients | TRPM8, TRPM7, TRPM2 | HTR1A 1163/4885POLB 4506/4885ALDH1A1 2466/4885 |
| US-20180093997-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM2 | HTR1A 1163/4885POLB 4506/4885ALDH1A1 2466/4885 |
| US-20120263659-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM2 | HTR1A 1163/4885POLB 4506/4885ALDH1A1 2466/4885 |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM5 | HTR1A 249/4885POLB 4708/4885ALDH1A1 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.