Benfuresate

Benfuresate

SCHEMBL7520848

C1CO1.CCS(=O)(=O)Oc1ccc2c(c1)C(C)(C)CO2

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
NOTUM Q6P988 2/20 0.38
RARB P10826 4/20 0.37
RARG P13631 4/20 0.37
RARA P10276 3/20 0.37
ALPI P09923 2/20 0.36
ALPL P05186 1/20 0.36
CA2 P00918 2/20 0.35
RXRA P19793 1/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP14 P50281 2/20 0.34
MMP7 P09237 1/20 0.34
HTR1A P08908 1/20 0.34
HTR2B P41595 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
ACACB O00763 1/20 0.33
CA12 O43570 1/20 0.33
ENPP3 O14638 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benfuresate SCHEMBL29396663 0.96 PTGS1 (0.41) PTGS1PTGS2NOTUMRARBRARG
Benfuresate SCHEMBL4890261 0.96 PTGS1 (0.41) PTGS1PTGS2NOTUMRARBRARG
Benfuresate SCHEMBL54959 0.96 PTGS1 (0.41) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11449645 0.87 CA12 (0.41) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11449273 0.85 PTGS1 (0.39) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11448349 0.85 ALPL (0.43) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL11459578 0.83 MMP2 (0.41) PTGS1PTGS2NOTUMRARBRARG
Benfuresate SCHEMBL15634059 0.83 ACACB (0.38) PTGS1PTGS2NOTUMRARBRARG
SCHEMBL18827241 0.83 PTGS1 (0.45) PTGS1PTGS2ALPIALPLCA2
SCHEMBL11450799 0.82 CA2 (0.45) PTGS1PTGS2NOTUMRARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002011538-A2 FLOATING TYPE FORMULATION OF AGRICULTURAL AGENTS BAYER CROPSCIENCE GMBH (DE) 2002-02-14 WO disclosed