Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497959 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KMT2AABCB11CYP1A1CYP1B1 | |
| SCHEMBL16973608 | 0.74 | ADH1B (0.41) | ALDH1A1KMT2ACYP1A1CYP1B1MTNR1A | |
| SCHEMBL10138510 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KMT2AABCB11CYP1A1CYP1B1 | |
| SCHEMBL113065 | 0.72 | L3MBTL1 (0.44) | ALDH1A1KMT2AMTNR1AMTNR1BPOLB | |
| SCHEMBL21465394 | 0.72 | L3MBTL1 (0.44) | ALDH1A1KMT2AMTNR1AMTNR1BPOLB | |
| SCHEMBL1133802 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL424239 | 0.72 | TAAR1 (0.47) | ALDH1A1 | |
| SCHEMBL15418608 | 0.69 | ALDH1A1 (0.46) | ALDH1A1KMT2AABCB11CYP1A1CYP1B1 | |
| SCHEMBL8853 | 0.69 | ALDH1A1 (0.46) | ALDH1A1KMT2ACYP1A1CYP1B1POLB | |
| SCHEMBL11183043 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KMT2AABCB11CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156059-B1 | Selectively cleavable linkers based on a methionine group and an ester group | AVENTIS PHARMA INC (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-0751779-B1 | SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS | SELECTIDE CORP (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-1156059-A1 | Selectively cleavable linkers based on a methionine group and an ester group | SELECTIDE CORPORATION (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0751779-A4 | SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS | SELECTIDE CORP (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0751779-A1 | SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS | SELECTIDE CORPORATION (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995000165-A1 | SELECTIVELY CLEAVABLE LINKERS BASED ON IMINODIACETIC ACID ESTER BONDS | SELECTIDE CORPORATION (US) | 1995-01-05 | — | — | WO | disclosed |